Open AccessPd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
Author(s) -
Longyang Dian,
Ilan Marek
Publication year - 2019
Publication title -
acs catalysis
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 4.898
H-Index - 198
ISSN - 2155-5435
DOI - 10.1021/acscatal.9b04960
Subject(s) - enantioselective synthesis , catalysis , chemistry , combinatorial chemistry , binap , organic chemistry
We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac) 2 and ( R )-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities.
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