Open AccessA Biocatalytic Aza-Achmatowicz Reaction
Author(s) -
Elena FernándezFueyo,
Sabry H. H. Younes,
Stefan van Rootselaar,
R. W. M. ABEN,
Rokus Renirie,
Ron Wever,
Dirk Holtmann,
Floris P. J. T. Rutjes,
Frank Hollmann
Publication year - 2016
Publication title -
acs catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.898
H-Index - 198
ISSN - 2155-5435
DOI - 10.1021/acscatal.6b01636
Subject(s) - catalysis , chemistry , bromide , vanadium , curvularia , reaction conditions , combinatorial chemistry , peroxidase , enzyme catalysis , organic chemistry , enzyme , food science , penicillium
A catalytic, enzyme-initiated (aza-) Achmatowicz reaction is presented. The involvement of a robust vanadium-dependent peroxidase from Curvularia inaequalis allows the simple use of H2O2 and catalytic amounts of bromide.
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