Cobalt(III)-Catalyzed Functionalization of Unstrained Carbon–Carbon Bonds through β-Carbon Cleavage of Alcohols | Zendy

Erhan Özkal | Zendy; Bastien Cacherat | Zendy; Bill Morandi | Zendy

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Cobalt(III)-Catalyzed Functionalization of Unstrained Carbon–Carbon Bonds through β-Carbon Cleavage of Alcohols

Author(s) -

Erhan Özkal,

Bastien Cacherat,

Bill Morandi

Publication year - 2015

Publication title -

acs catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.898

H-Index - 198

ISSN - 2155-5435

DOI - 10.1021/acscatal.5b01753

Subject(s) - catalysis , cobalt , chemistry , carbon fibers , electrophile , reinforced carbon–carbon , surface modification , cleavage (geology) , bond cleavage , aryl , combinatorial chemistry , organic chemistry , materials science , alkyl , fracture (geology) , composite number , composite material

We demonstrate that a simple Co(III)-complex can efficiently catalyze the cleavage of unstrained C-C bonds via the beta-carbon elimination of secondary and tertiary alcohols bearing a directing group. The cobalt-aryl intermediate generated under the reaction conditions can be trapped by different electrophiles to generate a new carbon carbon bond. Some essential features of this new Co-based mechanistic manifold were revealed by preliminary mechanistic studies

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