Fabrication of Carbohydrate-Conjugated Fingerprintlike Mesoporous Silica Net for the Targeted Capture of Bacteria | Zendy

Nanjing Hao | Zendy; Laifeng Li | Zendy; Fangqiong Tang | Zendy

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Fabrication of Carbohydrate-Conjugated Fingerprintlike Mesoporous Silica Net for the Targeted Capture of Bacteria

Author(s) -

Nanjing Hao,

Laifeng Li,

Fangqiong Tang

Publication year - 2016

Publication title -

acs applied materials and interfaces

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.535

H-Index - 228

eISSN - 1944-8252

pISSN - 1944-8244

DOI - 10.1021/acsami.6b10989

Subject(s) - conjugated system , mesoporous silica , materials science , mesoporous material , bacteria , staphylococcus epidermidis , bromide , nanotechnology , moiety , combinatorial chemistry , chemical engineering , organic chemistry , chemistry , catalysis , polymer , staphylococcus aureus , biology , engineering , composite material , genetics

Herein, a rapid, straightforward, reliable, and low-cost strategy for targeted capture and detection of bacteria using carbohydrate-conjugated mesoporous silica structure was developed. Fingerprint-like mesoporous silica net (FMSN) with well-defined three-dimensional architecture and ordered morphology was first facilely synthesized by the aid of tetrabutylammonium iodine (TBAI) as cotemplates with cetyltrimethylammonium bromide (CTAB). When conjugated with maltoheptaose as targeting moiety, FMSN showed efficient and selective capturing capability of Staphylococcus epidermidis. This new and unique platform for capturing S. epidermidis is fast (within 18 min), high efficiency (greater than 98.6% from 1 × 10 3 CFU/mL to 1 × 10 8 CFU/mL), specific (compared to M. smegmatis mc 2 155), and reusable (6 cycles).

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