Open AccessChemoselective Luche-Type Reduction of α,β-Unsaturated Ketones by Magnesium Catalysis
Author(s) -
Yoon Kyung Jang,
Marc Magre,
Magnus Rueping
Publication year - 2019
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/acs.orglett.9b03131
Subject(s) - chemistry , catalysis , magnesium , chemoselectivity , reduction (mathematics) , organic chemistry , reaction conditions , ketone , combinatorial chemistry , geometry , mathematics
The chemoselective reduction of α,β-unsaturated ketones by use of an economic and readily available Mg catalyst has been developed. Excellent yields for a wide range of ketones have been achieved under mild reaction conditions, short times, and low catalyst loadings (0.2-0.5 mol %).
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