Open AccessFormation of C(sp3)–C(sp3) Bonds by Palladium Catalyzed Cross-Coupling of α-Diazoketones and Allylboronic Acids
Author(s) -
MarieCharlotte Belhomme,
Dong Wang,
Kálmán J. Szabó
Publication year - 2016
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/acs.orglett.6b01132
Subject(s) - chemistry , palladium , catalysis , allylic rearrangement , coupling reaction , redox , medicinal chemistry , organic chemistry
Palladium catalyzed cross-coupling of allylboronic acids with α-diazoketones was studied. The reaction selectively affords the linear allylic product. The reaction proceeds with formation of a new C(sp(3))-C(sp(3)) bond. The reaction was performed without an external oxidant, likely without the Pd-catalyst undergoing redox reactions.
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