Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library | Zendy

Wojciech Drożdż | Zendy; Anna Walczak | Zendy; Artur R. Stefankiewicz | Zendy

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Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library

Author(s) -

Wojciech Drożdż,

Anna Walczak,

Artur R. Stefankiewicz

Publication year - 2021

Publication title -

organic letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.94

H-Index - 239

eISSN - 1523-7060

pISSN - 1523-7052

DOI - 10.1021/acs.orglett.1c01042

Subject(s) - chemistry , imine , dynamic covalent chemistry , covalent bond , disulfide bond , combinatorial chemistry , organic molecules , transesterification , organic chemistry , molecule , catalysis , supramolecular chemistry , biochemistry

Here we report the simultaneous formation of doubly and triply dynamic libraries as a result of exchange reactions between functionalized organic building blocks. A combination of three different reversible covalent linkages involving a boronate ester transesterification along with an imine and disulfide exchange was employed to generate a new type of fully organic triply dynamic molecular assembly.

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