Photocatalytic Palladium-Catalyzed Fluoroalkylation of Styrene Derivatives
Author(s) -
Réka Adamik,
Tamás Földesi,
Zoltán Novàk
Publication year - 2020
Publication title -
organic letters
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/acs.orglett.0c03043
Subject(s) - chemistry , palladium , catalysis , alkyl , styrene , heck reaction , photocatalysis , organic chemistry , combinatorial chemistry , palladium catalyst , photochemistry , copolymer , polymer
A visible light induced palladium-catalyzed fluoroalkylation method was developed. The Heck-type alkyl coupling reaction enables the introduction of trifluoroethyl, difluoroethyl and other fluoroalkyl fragment into styrenes under mild reaction conditions without the use of additional photosensitizers and ensures access to fluoroalkylated olefins on a broad scale.
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