Chemoselective Hydrogenation of Alkynes to (Z)-Alkenes Using an Air-Stable Base Metal Catalyst | Zendy

Viktoriia Zubar | Zendy; Jan Sklyaruk | Zendy; Aleksandra Brzozowska | Zendy; Magnus Rueping | Zendy

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Chemoselective Hydrogenation of Alkynes to (Z)-Alkenes Using an Air-Stable Base Metal Catalyst

Author(s) -

Viktoriia Zubar,

Jan Sklyaruk,

Aleksandra Brzozowska,

Magnus Rueping

Publication year - 2020

Publication title -

organic letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.94

H-Index - 239

eISSN - 1523-7060

pISSN - 1523-7052

DOI - 10.1021/acs.orglett.0c01783

Subject(s) - chemistry , bifunctional , catalysis , allylic rearrangement , manganese , ligand (biochemistry) , base (topology) , metal , cooperativity , reaction conditions , base metal , alkene , combinatorial chemistry , organic chemistry , mathematical analysis , biochemistry , materials science , receptor , mathematics , welding , metallurgy

A highly selective hydrogenation of alkynes using an air-stable and readily available manganese catalyst has been achieved. The reaction proceeds under mild reaction conditions and tolerates various functional groups, resulting in ( Z )-alkenes and allylic alcohols in high yields. Mechanistic experiments suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperativity.

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