Hydrogenation or Dehydrogenation of N-Containing Heterocycles Catalyzed by a Single Manganese Complex | Zendy

Viktoriia Zubar | Zendy; Jannik C. Borghs | Zendy; Magnus Rueping | Zendy

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Hydrogenation or Dehydrogenation of N-Containing Heterocycles Catalyzed by a Single Manganese Complex

Author(s) -

Viktoriia Zubar,

Jannik C. Borghs,

Magnus Rueping

Publication year - 2020

Publication title -

organic letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.94

H-Index - 239

eISSN - 1523-7060

pISSN - 1523-7052

DOI - 10.1021/acs.orglett.0c01273

Subject(s) - dehydrogenation , chemistry , catalysis , manganese , ligand (biochemistry) , metal , combinatorial chemistry , base (topology) , organic chemistry , mathematical analysis , biochemistry , receptor , mathematics

A highly chemoselective base-metal catalyzed hydrogenation and acceptorless dehydrogenation of N-heterocycles is presented. A well-defined Mn complex operates at low catalyst loading (as low as 2 mol %) and under mild reaction conditions. The described catalytic system tolerates various functional groups, and the corresponding reduced heterocycles can be obtained in high yields. Experimental studies indicate a metal-ligand cooperative catalysis mechanism.

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