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Evolution of a Manufacturing Route to Omarigliptin, A Long-Acting DPP-4 Inhibitor for the Treatment of Type 2 Diabetes
Author(s) -
John Y. L. Chung,
Jeremy P. Scott,
Camille Anderson,
Brian Bishop,
Nadine Bremeyer,
Yang Cao,
Qinghao Chen,
Robert C. Dunn,
Amude M. Kassim,
David Lieberman,
Aaron Moment,
Faye J. Sheen,
Michael J. Zacuto
Publication year - 2015
Publication title -
organic process research and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 109
eISSN - 1520-586X
pISSN - 1083-6160
DOI - 10.1021/acs.oprd.5b00267
Subject(s) - cycloisomerization , chemistry , pyrazole , reductive amination , dihydropyran , regioselectivity , combinatorial chemistry , isomerization , amination , stereocenter , stereochemistry , catalysis , organic chemistry , enantioselective synthesis

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