Open AccessMinimizing HCN in DIC/Oxyma-Mediated Amide Bond-Forming Reactions
Author(s) -
Marion Erny,
Marika Lundqvist,
Jon H. Rasmussen,
Olivier LudemannHombourger,
Frédéric Bihel,
Jan Pawlas
Publication year - 2020
Publication title -
organic process research and development
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 109
eISSN - 1520-586X
pISSN - 1083-6160
DOI - 10.1021/acs.oprd.0c00227
Subject(s) - chemistry , amide , solvent , hydrogen bond , dimethylformamide , adduct , peptide bond , medicinal chemistry , organic chemistry , molecule , enzyme
Aiming at advancing protocols for safer, environmentally sensible peptide synthesis we report our findings with regard to the occurrence of hydrogen cyanide (HCN, prussic acid) in amide bond-formin...
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom