Open AccessMorphology Control of Liposome - RAFT Oligomer Precursors to Complex Polymer Nanostructures
Author(s) -
MohammadAmin Moradi,
Sam Tempelaar,
Alex M. van Herk,
Johan P. A. Heuts
Publication year - 2019
Publication title -
macromolecules
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.994
H-Index - 313
eISSN - 1520-5835
pISSN - 0024-9297
DOI - 10.1021/acs.macromol.9b02182
Subject(s) - oligomer , raft , chain transfer , polymer chemistry , polymerization , acrylic acid , polymer , copolymer , acrylate , reversible addition−fragmentation chain transfer polymerization , vesicle , bromide , chemistry , materials science , chemical engineering , radical polymerization , membrane , organic chemistry , biochemistry , engineering
Different types of butyl acrylate (BA)- co -acrylic acid (AA) oligomers were synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization and mixed with extruded 200 nm dimethyldioctadecylammonium bromide vesicles. The resulting precursor structures form the basis for subsequent vesicle-templated polymerizations. Systematic variations in temperature, pH, oligomer length, and oligomer composition and their effects on precursor morphology were studied. Surprisingly, different morphologies were obtained, including capsules, protruded capsules, solid spheres, and multicompartment structures. For example, capsules and multicompartment structures were found to result from higher AA contents, and protruded capsules and solid particles resulted from lower AA contents. Subsequent chain extension of the RAFT oligomers resulted in polymer nanostructures resembling the precursor morphologies.
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