Open AccessDiscovery Proteomics for COVID-19: Where We Are Now
Author(s) -
Angela McArdle,
Kirstin E. Washington,
Blandine Chazarin Orgel,
Aleksandra Binek,
Danica-Mae Manalo,
Alejandro Rivas,
Matthew Ayres,
Rakhi Pandey,
Connor Phebus,
Koen Raedschelders,
Justyna Fert-Bober,
Jennifer E. Van Eyk
Publication year - 2021
Publication title -
journal of proteome research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.644
H-Index - 161
eISSN - 1535-3907
pISSN - 1535-3893
DOI - 10.1021/acs.jproteome.1c00475
Subject(s) - covid-19 , pandemic , coronavirus , proteomics , disease , autoimmunity , virology , pneumonia , immunology , betacoronavirus , biology , medicine , computational biology , infectious disease (medical specialty) , immune system , gene , pathology , genetics , outbreak
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible coronavirus responsible for the pandemic coronavirus disease 2019 (COVID-19), which has had a devastating impact on society. Here, we summarize proteomic research that has helped elucidate hallmark proteins associated with the disease with respect to both short- and long-term diagnosis and prognosis. Additionally, we review the highly variable humoral response associated with COVID-19 and the increased risk of autoimmunity.