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N-Acetylcolchinol Methyl Ether (a Natural Product); Suhailamine (a Phantom Natural Product)
Author(s) -
Stephen G. Davies,
Ai M. Fletcher,
Paul M. Roberts,
James E. Thomson,
Angus Yeung
Publication year - 2019
Publication title -
journal of natural products
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 139
eISSN - 1520-6025
pISSN - 0163-3864
DOI - 10.1021/acs.jnatprod.9b00595
Subject(s) - natural product , assertion , ether , product (mathematics) , imaging phantom , chemistry , stereochemistry , organic chemistry , computer science , medicine , mathematics , nuclear medicine , geometry , programming language
The reported characterization data for the allocolchicinoid alkaloid suhailamine, isolated from Colchicum decaisnei and known to have an erroneous structure, have been reanalyzed. This analysis has led to the current proposal that suhailamine has the same structure as N -acetylcolchinol methyl ether (NCME), an assertion that is supported by comparison with previously reported data for NCME. Suhailamine is therefore a phantom natural product, while NCME represents a naturally occurring allocolchicinoid rather than a purely synthetic entity.

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