Total Synthesis of the Proposed Structure of Penasulfate A: l-Arabinose as a Source of Chirality | Zendy

Yangguang Gao | Zendy; Zhou Cao | Zendy; Qiang Zhang | Zendy; Rui Guo | Zendy; Fei Ding | Zendy; Qingliang You | Zendy; Jingjing Bi | Zendy; Yongmin Zhang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Total Synthesis of the Proposed Structure of Penasulfate A: l-Arabinose as a Source of Chirality

Author(s) -

Yangguang Gao,

Zhou Cao,

Qiang Zhang,

Rui Guo,

Fei Ding,

Qingliang You,

Jingjing Bi,

Yongmin Zhang

Publication year - 2019

Publication title -

journal of natural products

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.976

H-Index - 139

eISSN - 1520-6025

pISSN - 0163-3864

DOI - 10.1021/acs.jnatprod.9b00245

Subject(s) - stereochemistry , total synthesis , olefin metathesis , yield (engineering) , chirality (physics) , sequence (biology) , olefin fiber , chemistry , enantioselective synthesis , metathesis , coupling (piping) , combinatorial chemistry , catalysis , organic chemistry , physics , biochemistry , materials science , nambu–jona lasinio model , chiral symmetry breaking , quantum mechanics , polymerization , thermodynamics , quark , polymer , metallurgy

The total synthesis of putative penasulfate A was effectively achieved by a convergent strategy with a longest linear sequence of 14 steps and overall yield of 8.6%. The highlights of our strategy involved an E -selective olefin cross-metathesis, Suzuki cross-coupling, and a copper(I)-catalyzed coupling reaction.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research