Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec | Zendy

Claudia Carpentier | Zendy; Emerson Ferreira Queiroz | Zendy; Laurence Marcourt | Zendy; JeanLuc Wolfender | Zendy; Jabrane Azelmat | Zendy; Daniel Grenier | Zendy; Stéphane Boudreau | Zendy; Normand Voyer | Zendy

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Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec

Author(s) -

Claudia Carpentier,

Emerson Ferreira Queiroz,

Laurence Marcourt,

JeanLuc Wolfender,

Jabrane Azelmat,

Daniel Grenier,

Stéphane Boudreau,

Normand Voyer

Publication year - 2017

Publication title -

journal of natural products

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.976

H-Index - 139

eISSN - 1520-6025

pISSN - 0163-3864

DOI - 10.1021/acs.jnatprod.6b00831

Subject(s) - lichen , dibenzofuran , chemistry , porphyromonas gingivalis , isolation (microbiology) , environmental chemistry , stereochemistry , microbiology and biotechnology , biology , botany , organic chemistry , bacteria , genetics

Chemical investigation of the methanol extract of the lichen Stereocaulon paschale collected in Nunavik, Canada, led to the isolation and identification of two new dibenzofurans (1 and 3) and 11 known lichen metabolites. The structures of the new compounds were established by analysis of 1D and 2D NMR spectroscopic and high-resolution mass spectrometric data. Herein, the first isolation of ascomatic acid dibenzofuran derivatives (1-3) from a whole lichen organism is reported. In addition, some of the isolated metabolites showed antibacterial activity against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans.

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