Open AccessThe Chimera That Curbs Appetite
Author(s) -
Leonard G. Luyt
Publication year - 2018
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.8b01809
Subject(s) - chemistry , chimera (genetics) , appetite , neuroscience , endocrinology , biochemistry , psychology , medicine , gene
A chimeric drug design approach, merging the structure of an antagonist and an inverse agonist, results in a new molecular scaffold for targeting the ghrelin receptor (GHSR).
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