Open AccessA Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs
Author(s) -
Irene Preet Bhela,
Alice Ranza,
Federica Carolina Balestrero,
M. Teresa Serafini,
Silvio Aprile,
Rita Maria Concetta Di Martino,
Fabrizio Condorelli,
Tracey Pirali
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c01218
Subject(s) - drug discovery , modular design , biochemical engineering , chemistry , proof of concept , synthetic biology , computer science , combinatorial chemistry , computational biology , engineering , programming language , biology , biochemistry , operating system