Open AccessTargeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure–Activity Relationship Insights and Evolution Perspectives
Author(s) -
Gabriele La Monica,
Alessia Bono,
Antonino Lauria,
Annamaria Martorana
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c01005
Subject(s) - chemistry , in silico , covalent bond , protease , covid-19 , computational biology , electrophile , structure–activity relationship , in vivo , enzyme , combinatorial chemistry , in vitro , biochemistry , stereochemistry , biology , catalysis , organic chemistry , gene , genetics , medicine , disease , pathology , infectious disease (medical specialty)
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