Polyphenols and Intestinal Permeability: Rationale and Future Perspectives | Zendy

Stefano Bernardi | Zendy; Cristian Del Bo’ | Zendy; Mirko Marino | Zendy; Giorgio Gargari | Zendy; Antonio Cherubini | Zendy; Cristina AndrésLacueva | Zendy; Nicole HidalgoLiberona | Zendy; Gregorio Peron | Zendy; Raúl GonzálezDomínguez | Zendy; Paul A. Kroon | Zendy; Benjamin Kirkup | Zendy; Marisa Porrini | Zendy; Simone Guglielmetti | Zendy; Patrizia Riso | Zendy

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Polyphenols and Intestinal Permeability: Rationale and Future Perspectives

Author(s) -

Stefano Bernardi,

Cristian Del Bo’,

Mirko Marino,

Giorgio Gargari,

Antonio Cherubini,

Cristina AndrésLacueva,

Nicole HidalgoLiberona,

Gregorio Peron,

Raúl GonzálezDomínguez,

Paul A. Kroon,

Benjamin Kirkup,

Marisa Porrini,

Simone Guglielmetti,

Patrizia Riso

Publication year - 2019

Publication title -

journal of agricultural and food chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.203

H-Index - 297

eISSN - 1520-5118

pISSN - 0021-8561

DOI - 10.1021/acs.jafc.9b02283

Subject(s) - polyphenol , intestinal permeability , dysfunctional family , in vivo , biology , computational biology , chemistry , microbiology and biotechnology , biochemistry , psychology , immunology , antioxidant , psychotherapist

Increasing evidence links intestinal permeability (IP), a feature of the intestinal barrier, to several pathological or dysfunctional conditions. Several host and environmental factors, including dietary factors, can affect the maintenance of normal IP. In this regard, food bioactives, such as polyphenols, have been proposed as potential IP modulators, even if the mechanisms involved are not yet fully elucidated. The aim of the present paper is to provide a short overview of the main evidence from in vitro and in vivo studies supporting the role of polyphenols in modulating IP and briefly discuss future perspectives in this research area.

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