Open AccessXylooligosaccharides Increase Bifidobacteria and Lachnospiraceae in Mice on a High-Fat Diet, with a Concomitant Increase in Short-Chain Fatty Acids, Especially Butyric Acid
Author(s) -
Karin Berger,
Stephen Burleigh,
Maria Lindahl,
Abhishek Bhattacharya,
Prachiti Patil,
Henrik Stålbrand,
Eva Nordberg Karlsson,
Frida Fåk Hållenius,
Margareta Nyman,
Patrick Adlercreutz
Publication year - 2021
Publication title -
journal of agricultural and food chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.203
H-Index - 297
eISSN - 1520-5118
pISSN - 0021-8561
DOI - 10.1021/acs.jafc.0c06279
Subject(s) - lachnospiraceae , butyric acid , prebiotic , inulin , food science , chemistry , cecum , short chain fatty acid , guar gum , fatty acid , dietary fiber , butyrate , biochemistry , biology , fermentation , firmicutes , 16s ribosomal rna , gene , ecology
Effects of xylooligosaccharides (XOSs) as well as a mixture of XOS, inulin, oligofructose, and partially hydrolyzed guar gum (MIX) in mice fed a high-fat diet (HFD) were studied. Control groups were fed an HFD or a low-fat diet. Special attention was paid to the cecal composition of the gut microbiota and formation of short-chain fatty acids, but metabolic parameters were also documented. The XOS group had significantly higher cecum levels of acetic, propionic, and butyric acids than the HFD group, and the butyric acid content was higher in the XOS than in the MIX group. The cecum microbiota of the XOS group contained more Bifidobacteria , Lachnospiraceae, and S24-7 bacteria than the HFD group. A tendency of lower body weight gain was observed on comparing the XOS and HFD groups. In conclusion, the XOS was shown to be a promising prebiotic candidate. The fiber diversity in the MIX diet did not provide any advantages compared to the XOS diet.