Quantitative Systems Toxicology Modeling To Address Key Safety Questions in Drug Development: A Focus of the TransQST Consortium | Zendy

Sofia Ferreira | Zendy; Ciarán Fisher | Zendy; Laura I. Furlong | Zendy; Loïc Laplanche | Zendy; Brian Kevin Park | Zendy; Carmen Pin | Zendy; Julio Sáez-Rodríguez | Zendy; Panuwat Trairatphisan | Zendy

Open Access

Quantitative Systems Toxicology Modeling To Address Key Safety Questions in Drug Development: A Focus of the TransQST Consortium

Author(s) -

Sofia Ferreira,

Ciarán Fisher,

Laura I. Furlong,

Loïc Laplanche,

Brian Kevin Park,

Carmen Pin,

Julio Sáez-Rodríguez,

Panuwat Trairatphisan

Publication year - 2020

Publication title -

chemical research in toxicology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.031

H-Index - 156

eISSN - 1520-5010

pISSN - 0893-228X

DOI - 10.1021/acs.chemrestox.9b00499

Subject(s) - key (lock) , drug development , data science , computer science , drug , toxicology , risk analysis (engineering) , medicine , pharmacology , biology , computer security

Omics data have been increasingly generated with limited demonstrated value in drug safety assessment. The TransQST consortium was launched to use omics and other data in mechanistic-based quantitative systems toxicology (QST) models to evaluate their potential use in species translation.

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