Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention
Author(s) -
Jiří Zavadil,
Steve Rozen
Publication year - 2019
Publication title -
chemical research in toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 156
eISSN - 1520-5010
pISSN - 0893-228X
DOI - 10.1021/acs.chemrestox.9b00339
Subject(s) - mutagenesis , computational biology , molecular epidemiology , epidemiology , carcinogen , cancer , biology , genetics , epidemiology of cancer , cancer prevention , bioinformatics , mutation , medicine , gene , pathology , breast cancer , genotype
Advances in experimental modeling of the mutational signatures of environmental exposures and endogenous mutagenic processes will elucidate the role of mutagenesis in cancer, facilitate carcinogen classification, and enable new molecular cancer epidemiology studies.
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