Open AccessKey Characteristics Approach to Carcinogenic Hazard Identification
Author(s) -
Kathryn Z. Guyton,
Linda Rieswijk,
Amy Wang,
Weihsueh A. Chiu,
Martyn T. Smith
Publication year - 2018
Publication title -
chemical research in toxicology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 156
eISSN - 1520-5010
pISSN - 0893-228X
DOI - 10.1021/acs.chemrestox.8b00321
Subject(s) - identification (biology) , key (lock) , hazard , carcinogen , hazard analysis , computer science , risk analysis (engineering) , engineering , business , biology , computer security , reliability engineering , genetics , ecology , botany
Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.
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