Open AccessAn Easily Available Ratiometric Reaction-Based AIE Probe for Carbon Monoxide Light-up Imaging
Author(s) -
Jianguo Wang,
Chunbin Li,
Qingqing Chen,
Hongfeng Li,
Lihua Zhou,
Xing Jiang,
Mengxue Shi,
Pengfei Zhang,
Guoyu Jiang,
Ben Zhong Tang
Publication year - 2019
Publication title -
analytical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.117
H-Index - 332
eISSN - 1520-6882
pISSN - 0003-2700
DOI - 10.1021/acs.analchem.9b02691
Subject(s) - chemistry , carbon monoxide , detection limit , fluorescence , aggregation induced emission , quenching (fluorescence) , nanotechnology , photochemistry , organic chemistry , chromatography , catalysis , physics , materials science , quantum mechanics
Carbon monoxide (CO) is a significant gasotransmitter that naturally modulates inflammatory responses. Visualization of CO in situ would help to reveal its physiological/pathological functions. Unfortunately, most existing CO fluorescent probes show aggregation-caused quenching (ACQ) properties. Herein, we report the reaction-based fluorescent probe (BTCV-CO) with aggregation-induced emission (AIE) characteristics for CO detection and imaging. This ratiometric AIE probe showed excellent stability, high sensitivity (detection limit of 30.8 nM), and superior selectivity. More importantly, this CO-responsive AIE probe could be facilely designed and easily obtained by two-step synthesis with high yield, providing an easy-to-handle AIE toolbox for real-time visualization of CO in a living system.
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