Chemical Imaging in Vivo: Photoacoustic-Based 4-Dimensional Chemical Analysis | Zendy

Chang Heon Lee | Zendy; Jeff Folz | Zendy; Joel W. Y. Tan | Zendy; Janggun Jo | Zendy; Xueding Wang | Zendy; Raoul Kopelman | Zendy

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Chemical Imaging in Vivo: Photoacoustic-Based 4-Dimensional Chemical Analysis

Author(s) -

Chang Heon Lee,

Jeff Folz,

Joel W. Y. Tan,

Janggun Jo,

Xueding Wang,

Raoul Kopelman

Publication year - 2019

Publication title -

analytical chemistry

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.117

H-Index - 332

eISSN - 1520-6882

pISSN - 0003-2700

DOI - 10.1021/acs.analchem.8b04797

Subject(s) - chemistry , photoacoustic imaging in biomedicine , in vivo , chemical imaging , nanotechnology , optics , remote sensing , physics , microbiology and biotechnology , materials science , hyperspectral imaging , biology , geology

We describe how 4-dimensional in vivo biochemical analysis can be performed using photoacoustic contrast nanoagents that have been designed to probe both structural and chemical information in vivo, enabling noninvasive, real time, spatially resolved chemical imaging. Early chemical imaging of a patient's tumor can inform the decision of effective treatment, regarding choices of chemotherapy, radiation, or immunotherapy.

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