Panoply of Fluorescence Polarization/Anisotropy Signaling Mechanisms for Functional Nucleic Acid-Based Sensing Platforms | Zendy

Sandrine Perrier | Zendy; Valérie Guieu | Zendy; Benoît Chovelon | Zendy; Corinne Ravelet | Zendy; Éric Peyrin | Zendy

Open Access

Panoply of Fluorescence Polarization/Anisotropy Signaling Mechanisms for Functional Nucleic Acid-Based Sensing Platforms

Author(s) -

Sandrine Perrier,

Valérie Guieu,

Benoît Chovelon,

Corinne Ravelet,

Éric Peyrin

Publication year - 2018

Publication title -

analytical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.117

H-Index - 332

eISSN - 1520-6882

pISSN - 0003-2700

DOI - 10.1021/acs.analchem.7b04593

Subject(s) - fluorescence anisotropy , chemistry , nucleic acid , polarization (electrochemistry) , anisotropy , fluorescence , homogeneous , nanotechnology , confusion , computational biology , biological system , biophysics , biochemistry , optics , statistical physics , psychology , physics , materials science , membrane , psychoanalysis , biology

Fluorescence polarization/anisotropy is a very popular technique that is widely used in homogeneous-phase immunoassays for the small molecule quantification. In the present Feature, we discuss how the potential of this signaling approach considerably expanded during the last 2 decades through the implementation of a myriad of original transducing strategies that use functional nucleic acid recognition elements as a promising alternative to antibodies.

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