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Smartphone-Powered Electrochemical Dongle for Point-of-Care Monitoring of Blood β-Ketone
Author(s) -
Jinhong Guo
Publication year - 2017
Publication title -
analytical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.117
H-Index - 332
eISSN - 1520-6882
pISSN - 0003-2700
DOI - 10.1021/acs.analchem.7b02531
Subject(s) - point of care , ketone bodies , chemistry , ketosis , spectrum analyzer , point of care testing , ketone , diabetic ketoacidosis , diabetes mellitus , nursing , medicine , biochemistry , pathology , computer science , organic chemistry , endocrinology , metabolism , telecommunications
A smartphone-powered medical dongle as a miniaturized electrochemical analyzer associated with an enzymatic β-hydroxybutyrate test strip for accurate characterization of blood ketone in peripheral whole blood at the point-of-care, which is capable of providing critical guidance for the evaluation and treatment of diabetic ketoacidosis (DK) and diabetic ketosis acid (DKA), is reported. The measured results of blood ketone by the medical dongle were compared with the clinical results from a bulky biochemical analyzer, and the analysis showed good agreement. The proposed medical smartphone-powered dongle was demonstrated to be a very promising platform as a miniaturized electrochemical analyzer for point-of-care monitoring of the critical biochemical parameters such as blood ketone and a good solution for mobile health management.

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