Liposome-Coated Persistent Luminescence Nanoparticles as Luminescence Trackable Drug Carrier for Chemotherapy | Zendy

Lijian Chen | Zendy; ChengXiong Yang | Zendy; XiuPing Yan | Zendy

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Liposome-Coated Persistent Luminescence Nanoparticles as Luminescence Trackable Drug Carrier for Chemotherapy

Author(s) -

Lijian Chen,

ChengXiong Yang,

XiuPing Yan

Publication year - 2017

Publication title -

analytical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.117

H-Index - 332

eISSN - 1520-6882

pISSN - 0003-2700

DOI - 10.1021/acs.analchem.7b01397

Subject(s) - persistent luminescence , luminescence , chemistry , liposome , autofluorescence , nanoparticle , drug delivery , drug carrier , nanotechnology , chemotherapy , biophysics , fluorescence , optoelectronics , optics , surgery , materials science , organic chemistry , biochemistry , physics , thermoluminescence , biology , medicine

Near-infrared persistent luminescence nanoparticles (NIR-PLNPs) are promising imaging agents due to deep tissue penetration, high signal-to-noise ratio, and repeatedly charging ability. Here, we report liposome-coated NIR-PLNPs (Lipo-PLNPs) as a novel persistent luminescence imaging guided drug carrier for chemotherapy. The Lipo-PLNP nanocomposite shows the advantages of superior persistent luminescence and high drug loading efficiency and enables autofluorescence-free and long-term tracking of drug delivery carriers with remarkable therapeutic effect.

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