Bioluminescence Probe for Detecting Hydrogen Sulfide in Vivo | Zendy

Bowen Ke | Zendy; Wenxiao Wu | Zendy; Wei Liu | Zendy; Hong Liang | Zendy; Deying Gong | Zendy; Xiaotong Hu | Zendy; Minyong Li | Zendy

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Bioluminescence Probe for Detecting Hydrogen Sulfide in Vivo

Author(s) -

Bowen Ke,

Wenxiao Wu,

Wei Liu,

Hong Liang,

Deying Gong,

Xiaotong Hu,

Minyong Li

Publication year - 2015

Publication title -

analytical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.117

H-Index - 332

eISSN - 1520-6882

pISSN - 0003-2700

DOI - 10.1021/acs.analchem.5b03636

Subject(s) - bioluminescence , chemistry , hydrogen sulfide , in vivo , endogeny , computational biology , nanotechnology , biochemical engineering , biophysics , biochemistry , microbiology and biotechnology , organic chemistry , sulfur , materials science , biology , engineering

Considering that hydrogen sulfide (H2S) is an endogenous signaling molecule involved in numerous biological processes, a method for monitoring H2S as a powerful tool for investigating its complicated functions and mechanisms is urgently demanded. Herein, a bioluminescent turn-on probe was reported based on caged strategy for the detection of H2S in vitro and in vivo. This probe will help us understand the intricate contribution of H2S to a variety of physiological and pathological processes.

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