Metaproteomics: Harnessing the Power of High Performance Mass Spectrometry to Identify the Suite of Proteins That Control Metabolic Activities in Microbial Communities
Author(s) -
Robert L. Hettich,
Chongle Pan,
Karuna Chourey,
Richard J. Gian
Publication year - 2013
Publication title -
analytical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.117
H-Index - 332
eISSN - 1520-6882
pISSN - 0003-2700
DOI - 10.1021/ac303053e
Subject(s) - metaproteomics , chemistry , mass spectrometry , suite , proteomics , biochemical engineering , computational biology , chromatography , environmental chemistry , biochemistry , archaeology , biology , gene , history , engineering
The availability of extensive genome information for many different microbes, including unculturable species in mixed communities from environmental samples, has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. To this end, metaproteomics exploits the power of high-performance mass spectrometry for extensive characterization of the complete suite of proteins expressed by a microbial community in an environmental sample.
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