Open AccessA two-dimensional quadrupole ion trap mass spectrometer
Author(s) -
Jae C. Schwartz,
Michael W. Senko,
John E. P. Syka
Publication year - 2002
Publication title -
journal of the american society for mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 127
eISSN - 1879-1123
pISSN - 1044-0305
DOI - 10.1016/s1044-0305(02)00384-7
Subject(s) - quadrupole ion trap , chemistry , mass spectrometry , ion , ion trap , quadrupole mass analyzer , hybrid mass spectrometer , ion trapping , trap (plumbing) , trapping , analytical chemistry (journal) , range (aeronautics) , selected ion monitoring , atomic physics , rod , quadrupole , excitation , selected reaction monitoring , tandem mass spectrometry , physics , chromatography , materials science , alternative medicine , ecology , gas chromatography–mass spectrometry , pathology , composite material , biology , quantum mechanics , medicine , organic chemistry , meteorology
The use of a linear or two-dimensional (2-D) quadrupole ion trap as a high performance mass spectrometer is demonstrated. Mass analysis is performed by ejecting ions out a slot in one of the rods using the mass selective instability mode of operation. Resonance ejection and excitation are utilized to enhance mass analysis and to allow isolation and activation of ions for MS(n) capability. Improved trapping efficiency and increased ion capacity are observed relative to a three-dimensional (3-D) ion trap with similar mass range. Mass resolution comparable to 3-D traps is readily achieved, including high resolution at slower scan rates, although adequate mechanical tolerance of the trap structure is a requirement. Additional advantages of 2-D over 3-D ion traps are also discussed and demonstrated.