Open AccessDetailed analysis of α,ω-bis(4-hydroxybutyl) poly(dimethylsiloxane) using GPC-MALDI TOF mass spectrometry
Author(s) -
E. Peter Maziarz,
X. Michael Liu,
Edmond T. Quinn,
YuChin Lai,
Daniel M. Ammon,
George L. Grobe
Publication year - 2002
Publication title -
journal of the american society for mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 127
eISSN - 1879-1123
pISSN - 1044-0305
DOI - 10.1016/s1044-0305(01)00347-6
Subject(s) - chemistry , mass spectrometry , prepolymer , trimethylsilane , matrix assisted laser desorption/ionization , mass spectrum , chromatography , gel permeation chromatography , time of flight mass spectrometry , analytical chemistry (journal) , desorption , polymer , ionization , adsorption , ion , polyurethane , organic chemistry
In this study the prepolymer alpha,omega-bis(4-hydroxybutyl) poly(dimethylsiloxane), used in the formulation of oxygen permeable films, is evaluated by gel permeation chromatography (GPC) combined with matrix assisted laser desorption ionization (MALDI) time of flight (TOF) mass spectrometry (MS). Two unexpected mass distributions are observed in the mass spectra. Reaction schemes for the formation of these distributions are proposed. A solution phase trimethylsilane end group modification was performed on the prepolymer to determine whether the unexpected mass distributions occur as impurities from synthesis or as artifacts from the MS process. Evaluation of the TMS modified prepolymer indicates the unexpected mass distributions indeed occur as impurities from the synthetic procedure. Average molecular weight values are determined by traditional GPC, direct MALDI-TOF MS, and GPC-MALDI-TOF MS methods and the results are compared.