Open AccessEndothelin gene variants and aortic and cardiac structure in never-treated hypertensives
Author(s) -
Malika Lajemi,
Sylvie Gautier,
Odette Poirier,
Jean-Philippe Baguet,
A Mimran,
Philippe Gosse,
Olivier Ha,
Carlos Labat,
François Cambien,
Athanase Bénétos
Publication year - 2001
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/s0895-7061(01)02162-8
Subject(s) - medicine , pulse wave velocity , arterial stiffness , cardiology , population , radial artery , candidate gene , endothelin 1 , endothelin receptor , endocrinology , artery , blood pressure , receptor , gene , genetics , biology , environmental health
The polymorphism of several candidate genes has been studied in relation to essential hypertension and cardiovascular complications. Target organ damage in essential hypertension is a complex disorder influenced by multiple genetic and environmental factors. The possible contribution of endothelin gene variants to target organ damage in hypertension in humans has not been studied in depth.