Open AccessDifferences in effects on DNA gyrase activity between two glutamate racemases of Bacillus subtilis , the poly‐γ‐glutamate synthesis‐linking Glr enzyme and the YrpC (MurI) isozyme
Author(s) -
Ashiuchi Makoto,
Kuwana Eriko,
Komatsu Kazuya,
Soda Kenji,
Misono Haruo
Publication year - 2003
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1016/s0378-1097(03)00381-1
Subject(s) - bacillus subtilis , isozyme , enzyme , dna gyrase , biochemistry , glutamate receptor , chemistry , biology , bacteria , genetics , gene , escherichia coli , receptor
Bacillus subtilis possesses two isogenes encoding glutamate racemases, the poly‐γ‐glutamate synthesis‐linking Glr enzyme and the YrpC isozyme, and produces abundant amounts of the Glr enzyme. The YrpC isozyme, but not the Glr enzyme, was found to influence the activity of DNA gyrase, as did the MurI‐type glutamate racemase of Escherichia coli , which is involved in peptidoglycan synthesis during cell division.