Open AccessThe ldb1 mutant of Saccharomyces cerevisiae is defective in Pmr1p, the yeast secretory pathway/Golgi Ca 2+ /Mn 2+ ‐ATPase
Author(s) -
Olivero Isabel,
Corbacho Isaac,
Hernández Luis M
Publication year - 2003
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1016/s0378-1097(03)00002-8
Subject(s) - complementation , saccharomyces cerevisiae , golgi apparatus , mutant , yeast , mutation , secretory pathway , phenotype , gene , biology , microbiology and biotechnology , genetics , chemistry , endoplasmic reticulum
The LDB1 gene of Saccharomyces cerevisiae was identified by complementation of the ldb1 mutant phenotype with a genomic library. We found that the ldb1 defect is complemented by PMR1 which codes for the yeast secretory pathway/Golgi Ca 2+ /Mn 2+ ‐ATPase. Besides that, the analysis of a null mutation of the PMR1 gene revealed a phenotype identical to that of ldb1 mutant. Thus, LDB1 must be considered a synonym of PMR1 .