Open AccessVitronectin is up-regulated after vascular injury and vitronectin blockade prevents neointima formation
Author(s) -
Pascale Dufourcq
Publication year - 2002
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1016/s0008-6363(01)00547-8
Subject(s) - neointima , vitronectin , alpha v beta 3 , integrin , downregulation and upregulation , beta (programming language) , extracellular matrix , apoptosis , chemistry , alpha (finance) , microbiology and biotechnology , medicine , biology , restenosis , receptor , biochemistry , surgery , construct validity , computer science , stent , patient satisfaction , gene , programming language
Smooth muscle cell (SMC) migration involves interactions with extracellular matrix (ECM) and is an important process in response to arterial wall injury. We investigated the expression and the functional role of vitronectin (VN) in the response after vascular injury.