Open AccessA protocol for ultra-high field laminar fMRI in the human brain
Author(s) -
Ke Jia,
Elisa Zamboni,
Catarina Rua,
Nuno Reis Goncalves,
Valentin G. Kemper,
Adrian K. T. Ng,
Christopher T. Rodgers,
Guy Williams,
Rainer Goebel,
Zoe Kourtzi
Publication year - 2021
Publication title -
star protocols
Language(s) - English
Resource type - Journals
ISSN - 2666-1667
DOI - 10.1016/j.xpro.2021.100415
Subject(s) - neuroimaging , computer science , protocol (science) , pipeline (software) , human brain , ultra high frequency , high resolution , artificial intelligence , neuroscience , psychology , medicine , geography , remote sensing , telecommunications , alternative medicine , pathology , programming language
Summary Ultra-high field (UHF) neuroimaging affords the sub-millimeter resolution that allows researchers to interrogate brain computations at a finer scale than that afforded by standard fMRI techniques. Here, we present a step-by-step protocol for using UHF imaging (Siemens Terra 7T scanner) to measure activity in the human brain. We outline how to preprocess the data using a pipeline that combines tools from SPM, FreeSurfer, ITK-SNAP, and BrainVoyager and correct for vasculature-related confounders to improve the spatial accuracy of the fMRI signal. For complete details on the use and execution of this protocol, please refer to Jia et al. (2020) and Zamboni et al. (2020) .
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