Polymorphism variant of MnSOD A16V and risk of female infertility in northern Iran | Zendy

Mostafa Pournourali | Zendy; Alireza Tarang | Zendy; Sarah Farzadi Haghighi | Zendy; Mostafa Yousefi | Zendy; Mohammad Hadi Bahadori | Zendy

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Polymorphism variant of MnSOD A16V and risk of female infertility in northern Iran

Author(s) -

Mostafa Pournourali,

Alireza Tarang,

Sarah Farzadi Haghighi,

Mostafa Yousefi,

Mohammad Hadi Bahadori

Publication year - 2016

Publication title -

taiwanese journal of obstetrics and gynecology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.518

H-Index - 35

eISSN - 1875-6263

pISSN - 1028-4559

DOI - 10.1016/j.tjog.2016.06.018

Subject(s) - genotype , infertility , allele , restriction fragment length polymorphism , oxidative stress , biology , genotype frequency , superoxide dismutase , male infertility , genetics , polymorphism (computer science) , andrology , medicine , immunology , gene , endocrinology , pregnancy

Infertility is a disease of the reproductive system defined by inability to conceive after having regular unprotected intercourse. Both environmental and genetic factors can be involved in female infertility. Manganese superoxide dismutase (MnSOD) is a crucial mitochondrial antioxidant enzyme that has a key role in cellular defense against agents that induce oxidative stress. The present study was aimed to evaluate the MnSOD A16V gene polymorphism in female infertility in northern Iran.

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