Gynecological and obstetric outcome in the French cohort of women with factor XIII deficiency | Zendy

Lucia Rugeri | Zendy; Christophe Martinaud | Zendy; Philippe Beurrier | Zendy; Yvonne Borg | Zendy; Hérvè Chambost | Zendy; Mirela Chirila-Hetsch | Zendy; Dominique Desprez | Zendy; Annie Harroche | Zendy; Vanessa Milien | Zendy; Brigitte PanPetesch | Zendy; Sandrine Meunier | Zendy

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Gynecological and obstetric outcome in the French cohort of women with factor XIII deficiency

Author(s) -

Lucia Rugeri,

Christophe Martinaud,

Philippe Beurrier,

Yvonne Borg,

Hérvè Chambost,

Mirela Chirila-Hetsch,

Dominique Desprez,

Annie Harroche,

Vanessa Milien,

Brigitte PanPetesch,

Sandrine Meunier

Publication year - 2020

Publication title -

thrombosis research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.184

H-Index - 112

eISSN - 1879-2472

pISSN - 0049-3848

DOI - 10.1016/j.thromres.2020.04.010

Subject(s) - medicine , factor xiii deficiency , miscarriage , factor xiii , obstetrics , abortion , pregnancy , incidence (geometry) , retrospective cohort study , gynecology , recurrent miscarriage , risk factor , vaginal bleeding , surgery , fibrinogen , physics , optics , biology , genetics

Congenital factor XIII deficiency is a very rare bleeding disorder affecting 33 patients in France. Besides its role in fibrin clot stabilization, factor XIII is involved in placental attachment. Fetal miscarriages represent a frequent and concerning issue for these patients. The aim of the present study was to describe clinical characteristics of women presenting severe congenital FXIII deficiency in France, to focus on gynecological and obstetrical events, and to report the management of these rare situations.

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