PI3Kβ-regulated β-catenin mediates EZH2 removal from promoters controlling primed human ESC stemness and primitive streak gene expression
Author(s) -
Sudhanshu Yadav,
António Garrido,
M. Carmen Hernández,
Juan Carlos Oliveros,
Vicente Pérez-García,
Mario F. Fraga,
Ana C. Carrera
Publication year - 2022
Publication title -
stem cell reports
Language(s) - English
Resource type - Journals
ISSN - 2213-6711
DOI - 10.1016/j.stemcr.2022.09.003
Subject(s) - biology , microbiology and biotechnology , embryonic stem cell , pi3k/akt/mtor pathway , repressor , epiblast , primitive streak , cellular differentiation , stem cell , transcription factor , gastrulation , genetics , gene , signal transduction
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