Open AccessEbola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes
Author(s) -
Whitney A Scoon,
Liliana Mâncio-Silva,
Ellen L. Suder,
Carlos Villacorta-Martín,
Jonathan Lindstrom-Vautrin,
John G. Bernbaum,
Steve Mazur,
Reed F. Johnson,
Judith Olejnik,
Elizabeth Flores,
Aditya Mithal,
Feiya Wang,
Adam J. Hume,
Joseph E. Kaserman,
Sandra March-Riera,
Andrew A. Wilson,
Sangeeta N. Bhatia,
Elke Mühlberger,
Gustavo Mostoslavsky
Publication year - 2022
Publication title -
stem cell reports
Language(s) - English
Resource type - Journals
ISSN - 2213-6711
DOI - 10.1016/j.stemcr.2022.08.003
Subject(s) - biology , transcriptome , bystander effect , ebola virus , downregulation and upregulation , virology , induced pluripotent stem cell , interferon , immune system , hepatocyte , viral replication , cxcl10 , immunology , virus , microbiology and biotechnology , gene , chemokine , gene expression , genetics , embryonic stem cell , in vitro