Open AccessHomozygous ALS-linked FUS P525L mutations cell- autonomously perturb transcriptome profile and chemoreceptor signaling in human iPSC microglia
Author(s) -
Sze Yen Kerk,
Yu Bai,
Janell Smith,
Pranav Lalgudi,
Charleen Hunt,
Junko Kuno,
John Nuara,
Tao Yang,
Kathryn Lanza,
Newton Chan,
Angel Coppola,
Qian Tang,
Jennifer Espert,
Henderson Jones,
Casey Fannell,
Brian Zambrowicz,
Eric Chiao
Publication year - 2022
Publication title -
stem cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.207
H-Index - 76
ISSN - 2213-6711
DOI - 10.1016/j.stemcr.2022.01.004
Subject(s) - biology , microglia , neurodegeneration , amyotrophic lateral sclerosis , transcriptome , microbiology and biotechnology , mutation , genetics , gene , immunology , gene expression , inflammation , disease , pathology , medicine
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