The Organoid Platform: Promises and Challenges as Tools in the Fight against COVID-19 | Zendy

Maarten H. Geurts | Zendy; Jelte van der Vaart | Zendy; Joep Beumer | Zendy; Hans Clevers | Zendy

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The Organoid Platform: Promises and Challenges as Tools in the Fight against COVID-19

Author(s) -

Maarten H. Geurts,

Jelte van der Vaart,

Joep Beumer,

Hans Clevers

Publication year - 2021

Publication title -

stem cell reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.207

H-Index - 76

ISSN - 2213-6711

DOI - 10.1016/j.stemcr.2020.11.009

Subject(s) - organoid , biology , covid-19 , computational biology , pandemic , virology , coronavirus infections , neuroscience , medicine , infectious disease (medical specialty) , disease , outbreak

Many pathogenic viruses that affect man display species specificity, limiting the use of animal models. Studying viral biology and identifying potential treatments therefore benefits from the development of in vitro cell systems that closely mimic human physiology. In the current COVID-19 pandemic, rapid scientific insights are of the utmost importance to limit its impact on public health and society. Organoids are emerging as versatile tools to progress the understanding of SARS-CoV-2 biology and to aid in the quest for novel treatments.

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