Open AccessRegenerative Medicine: Taming the Chimaera
Author(s) -
Bernard A.J. Roelen
Publication year - 2018
Publication title -
stem cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.207
H-Index - 76
ISSN - 2213-6711
DOI - 10.1016/j.stemcr.2018.09.003
Subject(s) - biology , chimera (genetics) , regenerative medicine , stem cell , induced pluripotent stem cell , immunology , immune system , microbiology and biotechnology , endothelial stem cell , embryonic stem cell , genetics , gene , in vitro
In this issue of Stem Cell Reports, Hamanaka et al. (2018) describe the generation of chimeric mice with all vascular endothelial cells derived from pluripotent stem cells. This approach is desirable to prevent immune rejection when human stem cells are combined with animal embryos to grow human organs in animals.
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