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pyIMD: Automated analysis of inertial mass measurements of single cells
Author(s) -
Andreas P. Cuny,
David MartinezMartin,
Gotthold Fläschner
Publication year - 2019
Publication title -
softwarex
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 21
ISSN - 2352-7110
DOI - 10.1016/j.softx.2019.100303
Subject(s) - python (programming language) , computer science , software , graphical user interface , raw data , computation , interface (matter) , computational science , software package , term (time) , data mining , real time computing , programming language , operating system , physics , bubble , quantum mechanics , maximum bubble pressure method
The total mass of single cells can be accurately monitored in real time under physiological conditions with our recently developed picobalance. It is a powerful tool to investigate crucial processes in biophysics, cell biology or medicine, such as cell growth or hydration dynamics. However, processing of the raw data can be challenging, as computation is needed to extract the mass and long-term measurements can generate large amounts of data. Here, we introduce the software package pyIMD that automates raw data processing, particularly when investigating non-migrating cells. pyIMD is implemented in Python and can be used as a command line tool or as a stand-alone version including a graphical user interface.

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