Atopic Dermatitis: Epidemiology and Pathogenesis Update | Zendy

Lawrence F. Eichenfield | Zendy; Charles N. Ellis | Zendy; Anthony J. Mancini | Zendy; Amy S. Paller | Zendy; Eric L. Simpson | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Atopic Dermatitis: Epidemiology and Pathogenesis Update

Author(s) -

Lawrence F. Eichenfield,

Charles N. Ellis,

Anthony J. Mancini,

Amy S. Paller,

Eric L. Simpson

Publication year - 2012

Publication title -

seminars in cutaneous medicine and surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.66

H-Index - 64

eISSN - 1558-0768

pISSN - 1085-5629

DOI - 10.1016/j.sder.2012.07.002

Subject(s) - atopic dermatitis , filaggrin , medicine , pathogenesis , skin barrier , epidemiology , dermatology , immunology , pathology

The prevalence of atopic dermatitis (AD) has increased markedly in the United States over the past 5 decades, with current reports varying from 10% to 20% prevalence in US children, and new diagnoses are estimated at almost 11% per year. Recent research in AD pathophysiology and pathogenesis has demonstrated that AD is associated with epidermal barrier dysfunction and that mutations in the filaggrin gene are implicated in barrier defects. These discoveries hold promise for future breakthroughs in the diagnosis and management of AD.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research