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Pruritus and Renal Failure
Author(s) -
Timothy G. Berger,
Martin Steinhoff
Publication year - 2011
Publication title -
seminars in cutaneous medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.66
H-Index - 64
eISSN - 1558-0768
pISSN - 1085-5629
DOI - 10.1016/j.sder.2011.04.005
Subject(s) - medicine , gabapentin , dialysis , disease , end stage renal disease , intensive care medicine , dermatology , pathology , alternative medicine
Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus. Topical and systemic agents as well as broadband ultraviolet phototherapy can be extremely beneficial. Gabapentin has been recently discovered as an effective agent for the patient with ESRD pruritus. Kappa opiate agonists are promising new therapeutic options.

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