Open AccessPresent status of sentinel lymph node biopsy in cervical cancer
Author(s) -
Ariel Glickman,
Sergio Valdés,
Blanca Gil-Ibáñez,
Pilar Paredes,
K. Cortes,
Aureli Angel Torné Blade
Publication year - 2018
Publication title -
reports of practical oncology and radiotherapy
Language(s) - English
Resource type - Journals
eISSN - 2083-4640
pISSN - 1507-1367
DOI - 10.1016/j.rpor.2018.04.004
Subject(s) - medicine , cervical cancer , sentinel lymph node , lymphedema , biopsy , sentinel node , radiology , stage (stratigraphy) , radical hysterectomy , radiation therapy , surgery , lymphadenectomy , lymph node , cancer , breast cancer , paleontology , biology
Cervical cancer is the fourth most common cancer in women, and seventh overall. This disease represents a medical, economic and social burden. In early FIGO stage patients (IA, IB1 and IIA1), nodal involvement is the most important prognostic factor. Imaging evaluation of nodal metastasis is of limited value. In order to determine lymph node involvement, allow loco-regional control of the disease, define the need for adjuvant radiotherapy and improve survival, standard surgery for early disease is radical hysterectomy with systematic pelvic lymphadenectomy. However, this surgical treatment has risks and complications: longer operative time, larger blood loss, neurovascular or ureteral injury, lower-limb lymphedema, symptomatic lymphocysts, hydronephrosis. A method that allows to define the presence of regional metastasis with less morbidity and equal or greater precision is particularly relevant. The use of the sentinel lymph node biopsy is intended to reach that purpose. The present study reviews recent literature on the role of sentinel lymph node biopsy in cervical cancer, analyzing its indications and contraindications, injection and detection techniques, tracers used, surgical and pathological approaches and its applicability in up-to-date clinical practice.